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Cheap cialis The complete physique clearance of vardenafil is fifty six L/h, and the terminal half-life of vardenafil and its main metabolite is approximately 4-5 hours. After oral administration, vardenafil is excreted as metabolites predominantly in the feces (approximately 91-95% of administered oral dose) and to a lesser extent within the urine (approximately 2-6% of administered oral dose). Therapeutic and supratherapeutic doses of vardenafil and the active control moxifloxacin produced comparable increases in QTc interval. cheap sildenafil.
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Cheap sildenafil Mean vardenafil plasma concentrations measured after the administration of a single oral dose of 20 mg to wholesome male volunteers are depicted in Figure 8. There was no impact on sperm motility or morphology after single 20 mg oral doses of vardenafil in wholesome volunteers. Because the disease state of sufferers requiring nitrate therapy is anticipated to increase the likelihood generic viagra of hypotension, the usage of vardenafil by sufferers on nitrate therapy or on nitric oxide donors is contraindicated . Vardenafil was secreted into the milk of lactating rats at concentrations roughly 10-fold larger than discovered in the plasma. Following a single oral dose of three mg/kg, 3.3% of the administered dose was excreted into the milk within 24 hours. No evidence of particular potential for teratogenicity, embryotoxicity or fetotoxicity was noticed in rats and rabbits that acquired vardenafil at up to 18 mg/kg/day throughout organogenesis. sildenafil 20mg.
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